Beta Cell Biology Consortium (BCBC)


At a Glance
  • Status: Completed Consortium
  • Year Launched: 2001
  • Initiating Organization: Vanderbilt University
  • Initiator Type: Academia
  • Disease focus:
    Type 1 Diabetes
  • Location: North America

Abstract

The Beta Cell Biology Consortium (BCBC) aims to facilitate research in the following areas and will be responsible for collaboratively generating the necessary reagents, mouse strains, antibodies, assays, protocols, technologies, and validation assays that are beyond the scope of any single research effort.

Mission

BCBC’s mission is to facilitate interdisciplinary collaborations to advance understanding of pancreatic islet development and function, with the goal of developing innovative therapies to correct the loss of beta cell mass in diabetes, including cell reprogramming, regeneration, and replacement.

Consortium History

BCBC was established by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health (NIH).

Structure & Governance

Activities within BCBC are overseen by both NIDDK staff members and participating scientists. A Steering Committee (SC), which consists of all BCBC principal investigators (PIs), meets on a semi-annual basis. An Executive Committee (EC) meets monthly by teleconference. An External Evaluation Committee serves to provide objective scientific input and guidance.

Financing

Currently, BCBC consists of more than 50 research laboratories, which are funded by U-01 cooperative agreements. Grant information can be found here: http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-01-014.html, http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-04-017.html, http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-04-018.html, and http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-09-011.html 

Impact/Accomplishment

Many of the BCBC investigator-initiated projects involve reagent-generating activities that will benefit the larger scientific community. The combination of programs and activities that together comprise BCBC should accelerate the pace of major new discoveries and progress within the field of beta cell biology.

Points of Contact

The Beta Cell Biology Consortium
Vanderbilt Center for Stem Cell Biology
2213 Garland Avenue
9465 MRB IV
Nashville, TN 37232-0494
phone: 615.936.8327
fax: 615.322.6645

Sponsors & Partners

Brigham and Women’s Hospital

Children’s Hospital of Philadelphia

Cincinnati Children’s Hospital Medical Center

CNRS – UMR 7225                                

Columbia University

Copenhagen University

DanStem, University of Copenhagen

Duke University Medical Center

Hadassah-Hebrew University Medical Center

Hagedorn Research Institute               

Harvard /HHMI

Hebrew University-Hadassah Medical School

Icahn School of Medicine at Mount Sinai

Imperial College London

Indiana University

Karolinska University

Massachusetts General Hospital

Massachusetts Institute of Technology

Max Planck Institute for Heart and Lung Research

McEwen Centre for Regenerative Medicine/ University Health Network

Mount Sinai School of Medicine

Northwestern University

Oregon Health & Sciences University

Phillips-Universität

Seattle Children’s Research Institute

Stanford University

The Jackson Laboratory                

The University of Chicago

University of California, Los Angeles

University of California, San Diego

University of California, San Francisco

University of Colorado

University of Geneva Faculty of Medicine

University of Massachusetts

University of Massachusetts Medical School

University of Massachusetts Medical School

University of Pennsylvania

University of Pittsburgh

University of Texas Southwestern Medical Center

University of Toronto

Vanderbilt University

Vanderbilt University Medical Center

Vrije Univesiteit, Brussels


Last Updated: 10/10/2016

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