At a Glance
  • Status: Completed Consortium
  • Year Launched: 2004
  • Initiating Organization: The Sanger Institute
  • Initiator Type: Industry
  • Disease focus:
    Cardiovascular
  • Location: Europe

Abstract

The Bloodomics project was implemented by the Sanger Institute with the aim of discovering novel gene regulating platelets. This is crucial to understanding what makes blood clots more likely in certain people and, in turn, could provide potential therapeutic targets for treatment of cardiovascular disease.  The Sanger Institute uses genome sequences to advance understanding of the biology of humans and pathogens to improve human health. 

Mission

The aims of the Bloodomics project were to discover genetic markers for the prediction of thrombus formation in coronary artery disease and to design anti-thrombotics for improved prevention treatment.  

Consortium History

Bloodomics began in June 2004 and ran for four years.  

Structure & Governance

Bloodomics was a consortium project of the Sanger Institute, which receives a recurrent core grant from the Wellcome Trust. The project built on a broad support from the partners' institutions and from other fund- providers across Europe, like the British and Dutch Heart Foundations and National Blood Services.

Financing

The Bloodomics project was funded with 9 million Euro through the 6th Framework Program of the European Union

Intellectual Property

HaemAtlas data (Watkins et al, Blood, 2009) and the platelet whole genome expression data of the Platelet Function cohort (Goodall et al, Blood, 2010) have been deposited with Array Express at EBI and the accession numbers can be found in the respective publications.

Impact/Accomplishment

Most recent publication regarding genetic markers found for blood clot may be viewed at http://www.sanger.ac.uk/about/press/2010/101126.html (Goodall et al, Blood, 2010)

Points of Contact

Main reception
Wellcome Trust Sanger Institute
Wellcome Genome Campus
Hinxton
Cambridge
CB10 1SA
UK
Tel: +44 (0)1223 834244
Fax: +44 (0)1223 494919
(Out of hours contact: +44 (0)1223 495015)


Last Updated: 06/19/2017

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