The ILSI Health and Environmental Science Institute (HESI)


At a Glance
  • Status: Completed Consortium
  • Year Launched: 1989
  • Initiating Organization: Health and Environmental Sciences Institute
  • Initiator Type: Government
  • No disease focus
  • Location: International

Abstract

The ILSI Health and Environmental Sciences Institute (HESI) is an independent, nonprofit institute within the International Life Sciences Institute (ILSI). HESI’s scientific programs bring together scientists from academia, industry, research institutes, foundations, and government agencies to identify and resolve global health and environmental issues.

Mission

HESI is a nonprofit institution whose mission is to engage scientists from academia, government, and industry to identify and resolve global health and environmental issues. As a neutral third-party organization, HESI acts as an objective forum for initiating dialogue among scientists with different perspectives and expertise, in the attempt to create a pathway that can resolve issues identified by its multisector membership and the external scientific community. HESI’s bylaws require that all HESI activities are directed and carried out in an objective manner for the benefit of the public health.

HESI was established in 1989 as an ILSI program and was later established in 1991 as an independent, charitable, and scientific institute affiliated to ILSI by means of a charter agreement. HESI’s purpose has been to provide an international forum to advance the understanding of scientific issues that could positively impact human health and/or the environment. The issue areas addressed by HESI’s programs have grown in scope and number since its inception in 1989.  At its inception, the organization had only one active project, approximately 15 sponsor companies, and approximately the same number of public-sector (academic and government) participants. As of 2013, HESI has representatives from 51 sponsor companies, 90 universities and research agencies, and 33 government agencies from more than a dozen countries around the world participating in HESI programs. HESI currently has 17 different scientific committees that execute close to 80 different research/collaborative activities across them.

Structure & Governance

HESI conducts its work through chartered scientific committees that involve academic, government, and industry scientists. HESI uses multisector scientific committees, managed by professional in-house scientific management staff, to define and address relevant research questions and make the findings available to the public. The organization’s bylaws require representation by the public and private sectors on all of its leadership teams and mandate that at least half of its Board of Trustees be from the public sector. Industry sponsors receive a single seat on the HESI Assembly, which allows them to participate in technical or project committees and to vote on a slate of candidates nominated by the Board to serve as trustees. 

The Board of Trustees is a 15- to 31-member board that serves as HESI’s governing body and is composed of a chair and vice chair employed by universities, government agencies, or other public bodies, while the president and vice president are drawn from employees of the sponsoring private sector organizations. The Board also appoints an Emerging Issues Committee to help identify new scientific issues and guide the overall scientific direction of the organization by utilizing a process that includes input from outside the organization and polls of its stakeholders. This committee also has the authority to nominate subcommittees to further evaluate scientific issues and make recommendations to the HESI Assembly. 

The Executive Committee oversees the operations in periods between the biannual Board meetings and includes, among others, the president, vice-president, chair, vice-chair, secretary, and treasurer. HESI is run by an executive director who reports to the president of the Board of Trustees and is a nonvoting member and officer of the Board and Executive Committees. Each project is staffed by one or more HESI project managers who provide professional scientific and administrative support to the programs. The projects are also required to identify public- and private-sector co-leaders or steering groups to help lead the project team in problem formulation, project execution, and communication of results on a volunteer basis.  

HESI’s scientific programs are conducted by multisector committees that organize, support, and execute collaborative laboratory research programs, workshops, conferences, literature reviews, training, and the development and analysis of databases. Project Committees focus on relatively specific tasks and are formed when subcommittees mature and become self-sufficient, or are created under the guidance of HESI’s Board of Trustees through special request from the sponsorship. The formation of Technical Committees for longer-term and broader or more comprehensive focus is also through approval of the Board of Trustees. Committees may exist for as little as one year or for a decade or longer depending on their scope and resources.

Financing

The majority of HESI’s scientific activity is supported through in-kind contributions of labor, experimental data, and expertise from public- and private-sector participants. Industry sponsors provide the primary financial support for HESI programs. However, HESI also receives financial and significant in-kind support from a variety of U.S. and international government agencies.

HESI’s annual sponsorship fees are based on sponsors’ worldwide sales (most recently available year-end figures). The HESI Board of Trustees determines annual dues for sponsorship (which currently range from $3,000 to $59,000) and support organization-wide strategic activities and execution of the Board and Emerging Issues Committees. Separate assessments are made for committee sponsorship and are set by the committee members on an annual basis.

Intellectual Property

The majority of HESI projects are within the precompetitive space, and thus intellectual property is typically not a concern. 

Data Sharing

Each HESI committee deals primarily with nonproprietary or public domain data, which are freely shared among the committee members. Publications by HESI committees are generally in peer-reviewed journals with public recognition of the fact that they constitute HESI work product. The outcomes of all HESI scientific programs are made publicly available.

HESI’s annual report, peer-reviewed publications, databases, and presentations at international scientific meetings serve as means of communicating findings to the broader scientific community. 

Sponsors & Partners

Syril Pettit, Executive Director

c/o HESI Branch Administrator, Cynthia Nobles

email: cnobles@hesiglobal.org

ILSI Health and Environmental Sciences Institute 

1156 15th Street, NW, Second Floor

Washington, DC 20005

Phone: 202-659-3306

Abbott Laboratories

Alkermes, Inc.

Amgen, Inc.

Amsterdam University

Astellas Pharma Inc.

AstraZeneca

Auburn University

Austrian Agency for Health and Food Safety

BASF Corp.

Battelle Memorial Institute

Bayer CropScience

Biogen Idec

BioReliance Corp.

Boehringer Ingelheim

Bristol-Myers Squibb

Brown University

California Environmental Protection Agency

ChanTest Corp.

Charles River Laboratories

Chevron Corp.

Coca-Cola Company

Colorado University

Columbia University

Cornell University

Covance

Daiichi-Sankyo, Ltd.

Data Sciences International, Inc.

Dow Chemical Company

Dow Corning

Duke University

DuPont

Eli Lilly & Co.

European Food Safety Authority

European Medicines Agency

Exiqon A/S

ExxonMobil Biomedical Sciences

F. Hoffmann-La Roche Ltd.

French Agency for the Safety of Health Products

GE Healthcare

George Washington University

Georgetown University

GlaxoSmithKline

Hamner Institute of Health Sciences

Harvard University

Health Canada

Imperial College London

Indiana University

Integrated Laboratory Systems

Janssen Pharmaceuticals

Johns Hopkins University

L’Oréal Corporation

Lisbon University

London School of Economics

LyondellBasell

Maccine Pte Ltd.

Mayo Clinic

Merck & Co., Inc.

Monsanto Company

National Center for Safety Evaluation of Drugs (China)

National Institute for Health Innovation (Japan)

National Institute of Health Sciences (Japan)

National Institutes of Health

National Institutes of Health/National Institute of Child Health and Human Development

National Institutes of Health/National Institute of Environmental Health Sciences

New York Medical College

Newcastle University

Norwegian Institute of Water Research

Novartis International AG

Ohio University

Osaka University

Pfizer, Inc.

Procter & Gamble Co.

Purdue Pharma L.P.

Quintiles

Roskilde University

Rutgers University

S.C. Johnson

Sanofi S.A.

Servier Laboratories

Shell Chemicals, Ltd.

Stellar Biotechnologies

Sumitomo Chemical Co., Ltd.

Swansea University

Syngenta, Ltd.

Takeda Pharmaceuticals

U.S. Army

U.S. Consumer Product Safety Commission

U.S. Department of Agriculture

U.S. Department of Commerce

U.S. Environmental Protection Agency

U.S. Food and Drug Administration

U.S. Geological Survey

University of Aachen

University of Aarhus

University of Arizona

University of California, Los Angeles

University of Guelph

University of Heidelberg

University of Illinois

University of Kansas

University of Leicester

University of Leuven

University of Liverpool

University of Miami

University of Michigan

University of Milan

University of Minnesota

University of Nebraska

University of North Texas

University of Ottawa

University of Queensland

University of South Carolina

University of Texas Houston

University of Toronto

University of Washington

University of Wisconsin

Utrecht University

Vanderbilt University

Vertex Pharmaceuticals

Virginia Commonwealth University

Virginia-Maryland Regional College of Veterinary Medicine

VisualSonics

Vrije Universiteit University Amsterdam

Wake Forest University

Weill Cornell Medical College


Last Updated: 04/08/2016

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