International Transporter Consortium (ITC)


At a Glance
  • Status: Active Consortium
  • Year Launched: 2009
  • Initiating Organization: American Society for Clinical Pharmacology and Therapeutics
  • Initiator Type: Third-party organization
  • No disease focus
  • Location: International

Abstract

Mission

The International Transporter Consortium (ITC) encourages dialogue in all sectors of transporter research to solidify our present understanding, challenge our current thinking, and position ourselves to better address the complex and critical issues related to transporters in drug development.

ITC’s goals are as follows:

Consortium History

October 2008: First workshop held; sponsored by U.S. Food and Drug Administration and Critical Path Initiative
March 2012: Second workshop focused on the status of transporters with emphasis on the role of multiple transporters in pharmaceutical research and development with a specific focus on potential clinical impact 

Impact/Accomplishment

ITC published its recommendations from the second workshop in the November 2012 issue of Clinical Pharmacology & Therapeutics. This manuscript provides the updated ITC transporter figure, a high-level summary of ITC2 recommendations, and a description of the upcoming series of white papers.

PMID: 23588305

Points of Contact

Lei Zhang
email: leik.zhang@fda.hhs.gov

Donald Tweedie
email: donald.tweedie@boehringer-ingelheim.com

Sponsors & Partners

Abbott

American Society for Clinical Pharmacology and Therapeutics

Boehringer Ingelheim Pharmaceuticals

Food and Drug Administration

Genentech

German Cancer Research Center

GlaxoSmithKline

Lilly Research Laboratories

Merck

Novartis

Pfizer

RIKEN Yokohama Institute

University of Arizona

University of California, San Francisco

University of Helsinki

University of Maryland

University of North Carolina at Chapel Hill

University of Tokyo

University of Western Ontario


Last Updated: 04/15/2016

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