BioMANufacturing Research Program (BioMAN)

At a Glance
  • Status: Active Consortium
  • Year Launched: 2007
  • Initiating Organization: Massachusetts Institute of Technology
  • Initiator Type: Academia
  • No disease focus
  • Location: North America


The Center for Biomedical Innovation (CBI) is addressing profound challenges in the global biomedical industry by developing, testing, and disseminating new knowledge and tools designed for real-world application through the following programs: Biomanufacturing Program (BioMAN), Consortium on Adventitious Agents in Biomanufacturing (CAACB), and New Drug Development Paradigms (NEWDIGS). CBI was established in 2005 and merged with Massachusetts Institute of Technology’s (MIT’s) Program on the Pharmaceutical Industry (POPI) in 2008. POPI was founded in 1991 with a major grant from the Alfred P. Sloan Foundation to promote research and educational activities on issues related to competitiveness, performance, and productivity in the pharmaceutical field.


CBI’s mission is to improve global health by overcoming obstacles to the development and implementation of biomedical innovation. CBI provides a safe and transparent environment for collaborative research among industry, academia, and government, and draws on the expertise of the MIT’s Schools of Engineering, Science, and Management, as well as the Harvard-MIT Division of Health Sciences and Technology (HST).

To address emerging biomanufacturing needs, BioMAN activities are focused on the following:

Consortium History

2005: CBI established
2008: CBI merged with MIT’s POPI

Structure & Governance

BioMAN Program Direction:

Stacy Springs, Ph.D.
BioMAN Director
phone: 617-253-3084

Paul W. Barone, Ph.D.
BioMAN Associate Director
phone: 617-253-9604

Anthony J. Sinskey, Sc.D.
Professor of Microbiology & Engineering Systems, Professor of Health Sciences and Technology, Harvard-MIT Health Division of Health Sciences, MIT

MIT Affiliated Faculty:

Thomas J. Allen, Ph.D., Howard W. Johnson Professor of Management, Emeritus Professor of Organization Studies, MIT Sloan School of Management
Richard D. Braatz, Ph.D., Edwin R. Gilliland Professor of Chemical Engineering
Jianzhu Chen, Ph.D., Cottrell Professor of Immunology; professor of biology
Charles L. Cooney, Ph.D., Robert T. Haslam Professor of Chemical Engineering
Jongyoon Han, Ph.D., Karl Van Tassel Associate Professor of Electrical Engineering; associate professor of biological engineering, Research Laboratory of Electronics
T. Alan Hatton, Ph.D., Ralph Landau Professor of Chemical Engineering Practice; director, David H. Koch School of Chemical Engineering Practice
Alexander M. Klibanov, Ph.D., Novartis Professor of Chemistry and Engineering
J. Christopher Love, Ph.D., associate professor of chemical engineering
Timothy K. Lu, MD, Ph.D., assistant professor of electrical engineering and computer science, Research Laboratory of Electronics
Stephen Miles, M.B.A., research affiliate, Center for Biomedical Innovation
Kristala Jones Prather, Ph.D., Theodore T. Miller Career Development Associate Professor of Chemical Engineering
Rajeev Ram, Ph.D., professor of electrical engineering and computer science
Ram Sasisekharan, Ph.D., Edward Hood Taplin Professor of Health Sciences & Technology and Biological Engineering; director, HST
Scott Stern, Ph.D., David Sarnoff Professor of Management of Technology; chair, Technological Innovation, Entrepreneurship, and Strategic Management Group, MIT Sloan School of Management
Michael Strano, Ph.D., associate professor of chemical engineering
Bernhardt L. Trout, Ph.D., professor, Department of Chemical Engineering; director, Novartis-MIT Center for Continuous Manufacturing
Mark R. Trusheim, Ph.D., visiting scientist, MIT Sloan School of Management
Kripa K. Varanasi, Ph.D., Doherty Chair in Ocean Utilization, associate professor of mechanical engineering
Joel Voldman, Ph.D., associate professor, Department of Electrical Engineering and Computer Science
Roy E. Welsch, Ph.D., professor of statistics and management science and engineering systems
Mehmet F. Yanik, Ph.D., associate professor of electrical engineering; High-Throughput Technology Group

Participating Institutions:

Georgetown University: Jeffrey T. Macher, Ph.D., associate professor, McDonough School of Business
Northeastern University: William S. Hancock, Ph.D., faculty fellow, Bradstreet Chair in Bioanalytical Chemistry; co-chair, Trans-NIH Alliance of Glycobiologists for Detection of Cancer and Cancer Risk; editor-in-chief, Journal of Proteome Research (ACS)
Rennselaer Polytechnic Institute: Steven M. Cramer, Ph.D., professor and William Weightman Walker Professor of Polymer Engineering, Department of Chemical and Biological Engineering
University of Prince Edward Island: Reuben Domike, Ph.D., MBA, assistant professor; research affiliate, MIT Center for Biomedical Innovation

Points of Contact

Stacy L. Springs, Ph.D.
Director, BioMAN
Executive Director, Consortium on Adventitious Agent Contamination in Biomanufacturing (CAACB)
phone: 617-253-3084

Sponsors & Partners

Alfred P. Sloan Foundation


Biogen Idec

EMD Millipore


Georgetown University


Latham Biopharm Group


Northeastern University




Sanofi Pasteur

U.S. Food and Drug Administration

University of Prince Edward Island

Last Updated: 04/06/2016

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