Clinical Pharmacogenetics Implementation Consortium (CPIC)
Research Areas
At a Glance
- Status: Active Consortium
- Year Launched: 2009
- Initiating Organization: PharmGKB
- Initiator Type: Industry
- No disease focus
- Location: International
Abstract
The Clinical Pharmacogenetics Implementation Consortium (CPIC) was formed in late 2009, as a shared project between PharmGKB and the Pharmacogenomics Research Network. CPIC guidelines are peer-reviewed and published in a leading journal (in partnership with Clinical Pharmacology and Therapeutics) with simultaneous posting to the PharmGKB website with supplemental information/data and updates. Anyone with clinical interests in pharmacogenetics is eligible for membership. CPIC’s goal is to address some of the barriers to implementation of pharmacogenetic tests in clinical practice.
Mission
CPIC develops guidelines designed to help clinicians understand how available genetic test results should be used to optimize drug therapy. These guidelines are evaluated on an ongoing basis and updated regularly with all changes posted to the PharmGKB website.
CPIC also includes a working group on informatics to address the growing interest in informatics aspects of CPIC guidelines and the clinical implementation of pharmacogenetics.
Consortium History
The guidelines were endorsed by the American Society of Health-System Pharmacists.
CPIC interacts with guidelines.gov, National Institutes of Health’s Genetic Testing Registry, PubMed, U.S. Food and Drug Agency, National Human Genome Research Institute’s Genomic Medicine Working Group, Institute of Medicine’s Genomic Medicine Roundtable, Pharmacogenomics Research Network, American Medical Informatics Association, and eMERGE.
Structure & Governance
CPIC Team
Impact/Accomplishment
Publications: https://www.pharmgkb.org/views/listPublications.action?projectId=74
Links/Social Media Feed
Points of Contact
Sponsors & Partners
Aegis Sciences Corporation |
AltheaDx, Inc. |
Astellas Pharma Global Development |
Baylor College of Medicine |
Cancer Treatment Centers of America |
Cedars-Sinai, Medical Center |
Cedars-Sinai, Medical Genetics Institute |
Center for Genomic Medicine, RIKEN/Institute of Biomedical Sciences, Academic Sinica, Taiwan |
Central South University, China |
Children’s Cancer Hospital-Egypt 57357 |
Children’s Mercy Hospital |
Cincinnati Children’s Hospital Medical Center |
Clalit Health Services, Haifa, Israel |
Clearview Cancer Institute |
Cleveland Clinic |
CompanionDx |
Dartmouth College |
Democritus University of Thrace Medical School |
Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart |
Erasmus University Medical Center Rotterdam |
Extremadura University Hospital, Spain |
Fairleigh Dickinson University School of Pharmacy |
Fullerton Genetics Center, Mission Health |
Geisinger Health System |
Genelex Corporation |
Genomics England |
Icahn School of Medicine at Mount Sinai |
Indiana University |
Indiana University and VA |
Instituto Nacional de Câncer |
Kaiser Permanente Colorado |
Kroger Pharmacy |
Lebanese American University, Lebanon |
Leiden University Medical Center |
Life Letters |
Luigi Sacco University Hospital, Italy |
Manchester University |
Mayo Clinic College of Medicine |
Medco Health Solutions, Inc. |
Medical College of Wisconsin |
Millennium Laboratories |
Moffitt Cancer Center |
Mount Sinai Medical School |
National Human Genome Research Institute |
National University of Singapore, YLL School of Medicine |
Newcastle University |
NIH Clinical Center/Laboratory for Informatics Development |
NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development |
NIH/National Cancer Institute |
NIH/National Center for Biotechnology Information |
NIH/National Heart, Lung, and Blood Institute |
NIH/National Human Genome Research Institute |
NIH/National Institute of General Medical Sciences |
NIH/National Institute on Drug Abuse |
NorthShore University Health Systems |
Odense University Hospital, University of Southern Denmark |
Ohio State University |
Omicia, Inc. |
Oregon Health and Science University |
Pennsylvania State University |
Pharmacogenomics Centre |
Radboud University Medical Center |
SA Pathology, Women’s and Children’s Hospital, Australia |
Sanford Healthcare |
Spanish National Cancer Centre |
SRI International |
St. Jude Children’s Research Hospital |
Stanford University |
Texas Tech University Health Sciences Center, Paul L. Foster School of Medicine |
The Geelong Clinic & Deakin University School of Medicine |
The Johns Hopkins University School of Medicine |
The University of Texas Health Science Center at Houston |
Translational Software |
U.S. Food and Drug Administration |
UH Program in Personalized Medicine and Targeted Therapeutics |
University at Buffalo, The State University of New York |
University of Alabama |
University of California, San Diego |
University of California, San Francisco |
University of Chicago |
University of Extremadura, Spain |
University of Florida |
University of Liverpool |
University of Ljubijana, Slovenia |
University of Malta |
University of Manchester |
University of Maryland |
University of Michigan College of Pharmacy |
University of Minnesota |
University of Pennsylvania |
University of Pittsburgh |
University of South Florida |
University of Toronto |
University of Toronto and CAMH |
University of Utah Health Care |
University Ulm |
Uppsala University |
Vanderbilt University |
Veterans Affairs San Diego Healthcare System |
Washington University in St. Louis |