Clinical Pharmacogenetics Implementation Consortium (CPIC)

At a Glance
  • Status: Active Consortium
  • Year Launched: 2009
  • Initiating Organization: PharmGKB
  • Initiator Type: Industry
  • No disease focus
  • Location: International


CPIC TitleThe Clinical Pharmacogenetics Implementation Consortium (CPIC) was formed in late 2009, as a shared project between PharmGKB and the Pharmacogenomics Research Network. CPIC guidelines are peer-reviewed and published in a leading journal (in partnership with Clinical Pharmacology and Therapeutics) with simultaneous posting to the PharmGKB website with supplemental information/data and updates. Anyone with clinical interests in pharmacogenetics is eligible for membership. CPIC’s goal is to address some of the barriers to implementation of pharmacogenetic tests in clinical practice.


CPIC develops guidelines designed to help clinicians understand how available genetic test results should be used to optimize drug therapy. These guidelines are evaluated on an ongoing basis and updated regularly with all changes posted to the PharmGKB website.

CPIC also includes a working group on informatics to address the growing interest in informatics aspects of CPIC guidelines and the clinical implementation of pharmacogenetics.

Consortium History

The guidelines were endorsed by the American Society of Health-System Pharmacists.

CPIC interacts with, National Institutes of Health’s Genetic Testing Registry, PubMed, U.S. Food and Drug Agency, National Human Genome Research Institute’s Genomic Medicine Working Group, Institute of Medicine’s Genomic Medicine Roundtable, Pharmacogenomics Research Network, American Medical Informatics Association, and eMERGE.

Structure & Governance


Points of Contact 

Sponsors & Partners

Aegis Sciences Corporation

AltheaDx, Inc.

Astellas Pharma Global Development

Baylor College of Medicine

Cancer Treatment Centers of America

Cedars-Sinai, Medical Center

Cedars-Sinai, Medical Genetics Institute

Center for Genomic Medicine, RIKEN/Institute of Biomedical Sciences, Academic Sinica, Taiwan

Central South University, China

Children’s Cancer Hospital-Egypt 57357

Children’s Mercy Hospital

Cincinnati Children’s Hospital Medical Center

Clalit Health Services, Haifa, Israel

Clearview Cancer Institute

Cleveland Clinic


Dartmouth College

Democritus University of Thrace Medical School

Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart

Erasmus University Medical Center Rotterdam

Extremadura University Hospital, Spain

Fairleigh Dickinson University School of Pharmacy

Fullerton Genetics Center, Mission Health

Geisinger Health System

Genelex Corporation

Genomics England

Icahn School of Medicine at Mount Sinai

Indiana University

Indiana University and VA

Instituto Nacional de Câncer

Kaiser Permanente Colorado

Kroger Pharmacy

Lebanese American University, Lebanon

Leiden University Medical Center

Life Letters

Luigi Sacco University Hospital, Italy

Manchester University

Mayo Clinic College of Medicine

Medco Health Solutions, Inc.

Medical College of Wisconsin

Millennium Laboratories

Moffitt Cancer Center

Mount Sinai Medical School

National Human Genome Research Institute

National University of Singapore, YLL School of Medicine

Newcastle University

NIH Clinical Center/Laboratory for Informatics Development

NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development

NIH/National Cancer Institute

NIH/National Center for Biotechnology Information

NIH/National Heart, Lung, and Blood Institute

NIH/National Human Genome Research Institute

NIH/National Institute of General Medical Sciences

NIH/National Institute on Drug Abuse

NorthShore University Health Systems

Odense University Hospital, University of Southern Denmark

Ohio State University

Omicia, Inc.

Oregon Health and Science University

Pennsylvania State University

Pharmacogenomics Centre

Radboud University Medical Center

SA Pathology, Women’s and Children’s Hospital, Australia

Sanford Healthcare

Spanish National Cancer Centre

SRI International

St. Jude Children’s Research Hospital

Stanford University

Texas Tech University Health Sciences Center, Paul L. Foster School of Medicine

The Geelong Clinic & Deakin University School of Medicine

The Johns Hopkins University School of Medicine

The University of Texas Health Science Center at Houston

Translational Software

U.S. Food and Drug Administration

UH Program in Personalized Medicine and Targeted Therapeutics

University at Buffalo, The State University of New York

University of Alabama

University of California, San Diego

University of California, San Francisco

University of Chicago

University of Extremadura, Spain

University of Florida

University of Liverpool

University of Ljubijana, Slovenia

University of Malta

University of Manchester

University of Maryland

University of Michigan College of Pharmacy

University of Minnesota

University of Pennsylvania

University of Pittsburgh

University of South Florida

University of Toronto

University of Toronto and CAMH

University of Utah Health Care

University Ulm

Uppsala University

Vanderbilt University

Veterans Affairs San Diego Healthcare System

Washington University in St. Louis

Last Updated: 04/14/2016

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