Human Toxicology Project Consortium

At a Glance
  • Status: Active Consortium
  • Year Launched: 2010
  • Initiating Organization: Humane Society
  • Initiator Type: Third-party organization
  • No disease focus
  • Location: North America


The Human Toxicology Project Consortium is a group of stakeholders currently drawn from the corporate and public interest communities that share the objective of accelerating implementation of a biological pathway-based approach to toxicology as described in the National Research Council’s 2007 report on “Toxicity Testing in the 21st Century.” The consortium aims to accelerate implementation of methods that result from these and other efforts by providing complementary support in three key areas: (a) addressing critical scientific needs not covered by current efforts, (b) communicating with stakeholders including nongovernmental organizations, government officials, and the public, and (c) providing an independent venue for lobbying and fundraising to support pathway-based science and policies.


The consortium’s mission is to serve as a catalyst for the prompt, global, and coordinated implementation of pathway-based toxicology, which will better safeguard human health and hasten the replacement of animal use in toxicology.

The consortium’s vision is a global paradigm shift to an in vitro approach to the risk assessment of chemicals and drugs that is based on a modern understanding of human biology and disease pathways, yielding results more rapidly and more predictive of human health effects than current approaches.

The consortium’s key aims are as follows:

Consortium History

2007: Consortium founded

Points of Contact

Contact the consortium coordinator:

Sponsors & Partners

Dow Chemical


Exxon Mobil

Humane Society International

Humane Society Legislative Fund

Humane Society of the United States

ILSI Health and Environmental Sciences Institute


Procter & Gamble

The Hamner Institutes

The Johns Hopkins  Center for Alternatives to Animal Testing

Toxicology Excellence for Risk Assessment


Last Updated: 05/24/2016

The Consortia-pedia Catalogue is a living resource, and we are always adding new consortia. Provide information here about your collaboration to apply to be included in the Catalogue.

All the information contained in the Consortia-pedia was collected from publically available sources. Decisions to include or exclude a particular listing from Consortia-pedia were also made on the basis of publically available information and the criteria outlined in the FAQs. This site is intended to be an objective resource for the community, and inclusion does not constitute or imply endorsement, recommendation, or approval by FasterCures or the Milken Institute.