International Molecular Exchange (IMEX) Consortium

At a Glance
  • Status: Active Consortium
  • Year Launched: 2007
  • Initiating Organization: European Commission Seventh Framework Programme (FP7)
  • Initiator Type: Government
  • No disease focus
  • Location: Europe


The International Molecular Exchange (IMEx) Consortium is a collaboration of public interaction data providers who are working to develop and curate a single interface for directly deposited interaction data and data from publications or peer-reviewed journals.


The IMEx consortium is an international collaboration between a group of major public interaction data providers who have agreed to share curation effort as well as the following:


IMEx is funded by the European Commission under PSIMEx, contract number FP7-HEALTH-2007-223411.

Intellectual Property

The IMEx Consortium is a collaboration between IntAct, DIP, MINT, MPIDB, MatrixDB, I2D, InnateDB, MPIDB, Swiss-Prot, and Molecular Connections. The IMEx Consortium applies the Creative Commons Attribution License ( This means that users are free to copy, distribute, display, and make commercial use of all IMEx records from the above databases provided appropriate credit is given. Appropriate credit should be given in the form of a URL linking the record to its original instance at the database that created it.

Data Sharing

IMEx partners all produce their own separate resources, which range from all-encompassing molecular interaction databases, such as those maintained by IntAct, MINT, and DIP, organism-centric resources, such as BioGrid or MPIDB, or biological domain centric, such as MatrixDB. However, they have committed to making records available, via a dedicated PSICQUIC web service, which have been curated to IMEx rules and are available to the user as a single, nonredundant set of curated publications that can be searched at the IMEx website. The dataset will automatically increase with every release by a participating, member database. Data are made available in standards-compliant, tab-delimited, and XML formats, enabling users to visualize the data in a wide range of tools such as Cytoscape and the R Bioconductor software. In the short term, data redundancy will be managed by ensuring that partners only contribute records from a selected list of journals or from direct submission by authors as part of the publication process. This will shortly be replaced by an internal data management system that will allow a much greater range of journal articles to be made available to the user.

Sponsors & Partners


Database of Interacting Proteins (DIP)


IntAct Molecular Interaction Database

Interologous Interaction Database


Molecular Connections

Molecular INTeraction Database

Swiss-Prot Group

The Extracellular Matrix Interaction Database (MatrixDB)

Last Updated: 04/15/2016

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