Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT)

At a Glance
  • Status: Completed Consortium
  • Year Launched: 2002
  • Initiating Organization: University of Washington
  • Initiator Type: Academia
  • Disease focus:
  • Location: North America



The mission of the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) is to develop consensus reviews and recommendations for improving the design, execution, and interpretation of clinical trials of treatments for pain.

Consortium History

The first IMMPACT meeting was held in November 2002, and there have been a total of 17 consensus meetings on clinical trials of treatments for acute and chronic pain in adults and children.

Structure & Governance

Effective July 1, 2011, IMMPACT consensus meetings, publications, and other activities will be conducted under the auspices of the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION) public-private partnership with the U.S. Food and Drug Administration.

IMMPACT recommendations and systematic reviews have been widely cited and have guided the design of clinical trials, other types of clinical research, and a national survey. Additional consensus meetings are planned, and research initiatives involving the assessment of pain and the design and interpretation of clinical trials are ongoing. IMMPACT has received favorable responses from all of its stakeholders, who believe that this multidisciplinary initiative has made significant contributions to improved understanding of pain and its treatment.

Sponsors & Partners



Centrexion Corporation

Collegium Pharmaceutical


Horizon Pharma

Jazz Pharmaceuticals

Johnson & Johnson


Olatec Industries LLC





Last Updated: 04/15/2016

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