Identification of new types of biomarkers and tracers for the in vivo molecular imaging of the pancreatic Beta-cell mass (KeyMarker)

At a Glance
  • Status: Completed Consortium
  • Year Launched: 2011
  • Initiating Organization: IBA Group
  • Initiator Type: Industry
  • Disease focus:
    Type 2 Diabetes
  • Location: Europe



The goal of KeyMarker is to identify molecules that can be used as radiotracers for positron emission tomography (PET) or single-photon emission computed tomography (SPECT) imaging and potential quantification of the pancreatic beta-cell mass. Such molecules may lead to novel approaches for diabetic disease management, such as patient stratification, disease follow-up, and therapeutic options. Several ligands for the target will be screened and evaluated through the preclinical models developed for the project. The in vitro/in vivo preclinical platform as well as the toxicology, bio-distribution, and labeling expertise dedicated to the project form the basis for a standard process for further diabetes imaging tracer evaluation.


This was a three-year project with a total budget of €2.7 million.

Points of Contact

Richard Zimmermann (project coordinator)

Sponsors & Partners








Last Updated: 04/15/2016

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