At a Glance
  • Status: Completed Consortium
  • Year Launched: 2009
  • Initiating Organization: European Comission
  • Initiator Type: Government
  • Disease focus:
    Streptococcus pneumonaie
  • Location: Europe

Abstract

The singularity of Pneumopath lies in its multi-faceted approach, its breadth of study of bacterial strains and of individual susceptibility and its computational analysis. The project comprised six distinct but overlapping scientific “workpackages” with different objectives.

Workpackage 1: study of molecular epidemiology and genetic characterization of antibiotic susceptible and resistant pneumococcal isolates.

Workpackage 2: study into the identification of new host loci conferring innate resistance in invasive pneumococcal disease.

Workpackage 3: definition of parameters of pneumococcal infection in the animal host.

Workpackage 4: a study into the definition of parameters of pneumococcal infection in in vitro cell culture models.

Workpackage 5: a study of the features of the central metabolism of Steptococcus pneumonaie.

Workpackage 6:  the development of a shared data repository and dedicated data processing facilities for the subsequent analysis of project data.

Mission

The aim of the project was to comprehensively study the host-pathogen interactions during infection of Streptococcus pneumonaie with the objective of finding new targets for diagnosis and treatment. It built on the existing expertise gained by the project partners and on the knowledge gained through previous EU-funded research in earlier framework programmes, namely PREVIS, LMTOCHE, PNEUMOPEP, and DRESP2.

Structure & Governance

The project was coordinated by the University of Leicester and managed by Professor Peter Andrew, Head of the Department of Infection, Immunity, and Inflammation.

Financing

The Pneumopath project is an EU-funded, health-themed, collaborative research project within the seventh framework programme

Data Sharing

The University of Leicester Website, as a database, is eligible for protection under copyright and Database Right. These rights are owned by the University of Leicester.

Impact/Accomplishment

To view publications acknowledging the Pneumopath Project, click here

Points of Contact

PNEUMOPATH Project Administrator

Department of Infection, Immunity and Inflammation, University of Leicester, Maurice Shock Building, University Road, Leicester LE1 9HN

T: +44(0)116 2523063

E: Pneumopath@le.ac.uk

Sponsors & Partners

University of Leicester, UK (ULEIC)

CNRS Université Paul Sabatier, Toulouse, France (CNRS)

Radboud Universiteit, Nijmegen, Netherlands (RUNMC)

Smittskyddinstitutet, Solna, Sweden (SMI)

Islensk Erfdageining EHF, Reykjavik, Iceland (DECOD)

Università degli Studi di Siena, Italy (UNISI)

Technische Universität Kaiserslautern, Germany (UKAIS)

Universidade Nova de Lisboa, Oeiras, Portugal (ITQB)

Biomolecular Sciences and Biotechnology Institute, Rijksuniversiteit Groningen, The Netherlands (UGRON)

Institut National des Sciences Appliquées, Toulouse, France (INSA)

Universidade Técnica de Lisboa, Portugal (INESC-ID)

Intercell AG, Vienna, Austria (IC)

MRC Mammalian Genetics Unit, Oxfordshire, UK (MRCMGU)

Karolinska Institutet, Solna, Sweden (KI)

IQ Corporation, Groningen, The Netherlands (IQT)


Last Updated: 06/20/2017

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