PROteomics SPECification in Time and Space
Research Areas
At a Glance
- Status: Completed Consortium
- Year Launched: 2008
- Initiating Organization: European Commission Seventh Framework Programme (FP7)
- Initiator Type: Government
- No disease focus
- Location: Europe
Abstract
The PROteomics SPECification in Time and Space (PROSPECTS) consortium aims to advance the development of instruments and methods for proteomics. The goal is to annotate quantitatively the human proteome with respect to protein localization and dynamics. PROSPECTS also offers training opportunities teaching state-of-the-art technology for young scientists.
Mission
The PROSPECTS (PROteomics SPECification in Time and Space) consortium aims to develop instrumentation and methods to advance proteomics efforts with a goal to annotate quantitatively the human proteome with respect to protein localization and dynamics. Complementary technologies, including mass spectrometry, cryoelectron microscopy, and cell imaging will be used to capture transient protein complexes and the spatial and temporal dimensions of entire proteomes. The consortium aims to develop new proteomics technologies in a generic fashion to maximize their utility to the wider biomedical community.
Comprehensive data sets generated in PROSPECTS are aimed to broadly advance the field of proteomics. The multi-dimensional data sets generated in PROSPECTS will be integrated using advanced data aggregation and machine learning. The data will be available to the scientific community via annotated online public databases and used as a basis for a systems biological modelling of the human proteome with spatial and temporal resolution within the cell.
Sponsors & Partners
Max Planck |
Eidgenoessische Technische Hochschule, Zurich |
University of Cambridge (UK) |
Syddansk Universitet (University of Southern Denmark) |
Thermo Fisher Scientific |
Proxeon Biosystems (Denmark) |
Centre de Regulacio Genomica (Barcelona) |
University of Dundee (UK) |
Kungliga Tekniska Hoegskolan (Stockholm) |
Hebrew University (Jerusalem) |
University of Oxford |